What is MFAT Therapy?

Microfragmented Adipose Tissue (MFAT) therapy uses regenerative cells naturally found in your body’s fat tissue to support healing in joints, tendons, and other musculoskeletal structures.

Through a minimally invasive procedure, fat tissue is harvested, processed to preserve cell viability, and precisely injected where your body needs healing support. At Palm Beach Regenerative, Dr. Ghattas offers MFAT as an alternative or complement to bone marrow concentrate for carefully selected patients.

Adipose tissue contains a rich population of regenerative cells, growth factors, and supporting structures that work together to support tissue healing.

How MFAT Treatment Works

  1. Fat Harvest
    A small amount of fat is harvested from your abdomen or flank using local anesthesia and a small cannula. The harvest is gentle and well-tolerated with minimal discomfort.
  2. Laboratory Processing
    Fat tissue is processed in a sterile closed system using gentle microfragmentation. This minimal processing preserves the natural structure and viability of cells.
  3. Image-Guided Injection
    Using ultrasound or fluoroscopic guidance, Dr. Ghattas precisely injects MFAT to target structures in joints, tendons, or other tissues.

Total Time: Plan for 2.5-3 hours for complete visit.

Conditions Treated With MFAT

MFAT therapy may help patients with:

Joint Conditions:

  • Knee osteoarthritis (mild-moderate)
  • Hip osteoarthritis (select candidates)
  • Shoulder arthritis
  • Small joint arthritis

Tendon Conditions:

  • Rotator cuff tears (partial)
  • Achilles tendinopathy
  • Chronic tendon degeneration

Other Applications:

  • Ligament injuries
  • Cartilage damage
  • Chronic inflammation
  • Conditions requiring substantial cell populations

What Makes MFAT Different?

Alternative Cell Source:
For patients where bone marrow harvest is not ideal, MFAT provides another option using fat tissue.

Abundant Cell Population:
Fat tissue contains high concentrations of regenerative cells in a small volume.

Minimally Invasive Harvest:
Fat harvest via small cannula is generally well-tolerated with minimal discomfort.

Preserved Natural Structure:
Minimal processing maintains cells in their natural environment, potentially preserving function.

What to Expect After MFAT Treatment

Immediate (Day 0-3):

  • Mild soreness at harvest site (similar to minor bruise)
  • Some swelling or discomfort at injection site
  • Ice and compression as directed
  • Return to light activities day 1-2

Early Phase (Week 1-4):

  • Harvest site heals quickly (usually within 1 week)
  • Injection site inflammation part of healing response
  • Begin gentle exercises as directed

Regeneration Phase (Week 4-12):

  • Gradual improvement in symptoms
  • Tissue healing and remodeling continues
  • May be combined with physical therapy or MLS Laser

Maturation Phase (3-6 months):

  • Continued improvement
  • Full tissue remodeling takes several months
  • Follow-up assessment and imaging

Activity Restrictions:

  • Avoid high-impact activities: 4-8 weeks
  • Gradual return to sport/activity
  • Specific guidelines based on condition

Success Rates and Outcomes

Based on published research and clinical experience, many patients report:

  • Meaningful reduction in joint pain
  • Improved function and mobility
  • Enhanced quality of life
  • Delayed or avoided surgical intervention

Important: Results vary based on severity of arthritis/injury, age, overall health, adherence to rehabilitation, and individual healing capacity.

Is MFAT Right for You?

MFAT may be appropriate when:

  • You have moderate joint arthritis or significant tendon damage
  • Bone marrow harvest is not ideal for you
  • You want substantial cell population for healing
  • You prefer fat-based approach

MFAT vs. Bone Marrow Concentrate:

  • Both contain regenerative cells with healing potential
  • Harvest procedures differ (fat vs. bone marrow)
  • Dr. Ghattas will recommend best option for your situation

MFAT vs. PRP/SCP:

  • MFAT contains cells, not just growth factors
  • MFAT may be considered for more severe conditions
  • Recovery timelines differ

Why Choose Palm Beach Regenerative for MFAT?

  • Minimally invasive gentle harvest technique
  • Sterile closed-system processing
  • Image-guided precision placement
  • Fellowship-trained physician
  • Systematic outcome tracking
  • Can be combined with other treatments

Cost and Insurance

Most insurance plans do not cover MFAT therapy. We provide:

  • Transparent pricing before commitment
  • Itemized treatment plan
  • Superbills for possible reimbursement
  • HSA/FSA eligible
  • CareCredit financing options
Required Disclaimer

Like all medical procedures, MFAT therapy has potential risks and benefits. Results vary by individual based on condition severity, overall health, and healing response. Not all patients are candidates. Dr. Ghattas will discuss realistic expectations and all treatment options, including when surgery may be more appropriate.

Schedule a consultation to discuss MFAT treatment.

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No medical procedure can guarantee an outcome. What you should expect is an honest discussion of the evidence, a careful assessment of candidacy, and a recommendation based on your condition.

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